The Interaction of Stomach Acid, Blood pH, and Liver Metabolism with Acidic Cannabinoids: Partial Decarboxylation, Metabolic Transformation, and Physiological Implications (2025)

Acidic cannabinoids (e.g., THCA, CBDA) are the dominant phytoconstituents in Cannabis Sativa and serve as precursors to neutral forms (THC, CBD) via decarboxylation. This is the third work in an integrated series exploring how dietary cannabis inputs interact with the Endocannabinoid System (ECS) pa