Hemp Research — Page 9

Peer-reviewed industrial hemp research papers, sorted by publication date. Browse the latest findings on hemp cultivation, processing, materials science, biomedical applications, and regulatory science from PubMed, OpenAlex, and other indexed sources.

Major CYP450 Polymorphism among Saudi Patients (2021)

Background: Cytochrome P450 (CYP) contributes to a huge collection of medicinal products' Phase I metabolization. We aimed to summarize and investigate the current evidence regarding the frequency of CYP2D6, CYP2C9, CYP2C19, and MDR1 in Saudi Arabia. Methods: A computerized search in four databases was done using the relevant keywords. The screening process was done in two steps; title and abstract screening and full-text screening. Data of demographic and characteristics of included studies

CYP450 Metabolism of a Semisynthetic Naphthoquinone, an Anticancer Drug Candidate, by Human Liver Microsomes (2022)

CNFD (6b,7-dihydro-5H-cyclopenta[b]naphtho[2,1-d]furan-5,6(9aH)-dione) is a semisynthetic naphthoquinone derived from lawsone that has cytotoxic action in different tumor lines and anticancer activity in vivo. Therefore, this molecule is a relevant candidate for drug development, but there is still no information on its human metabolism and systemic elimination. This study aimed to investigate the in vitro metabolism of this naphthoquinone by human liver microsomes. Initially, in order to determ

The Pharmacokinetic and Pharmacodynamic Drug-drug Interaction Potential of Cannabidiol (2025)

<p>Although Cannabidiol (CBD) has recently been approved for use in some neurological diseases, the pharmacology of CBD is not fully understood. Experimental reports suggest CBD inhibits a large number of enzymes, generating the possibility of multiple interactions. The aim is to describe the main known interactions, evidence, and actual risk in clinical practice. Existing indexed publications and product monographs were reviewed. The authors catal

Capacity of the Human Gut Microbiome in Metabolism of Drugs and Its Interaction with CYP450 Enzymes (2024)

As a promising field of pharmaceutical sciences, gut microbiome effects on metabolism of xenobiotics, has shown great potential to be considered as a milestone. Xenobiotic chemistries are modified by some drug metabolizing enzymes in gut microbiome which are mostly unknown, however their functionality and the way they impose changes on drug structures are well known. Most of the drug metabolizing enzymes in gut microbial population have reductor effects which are in contrary to the host metaboli

Physical and mechanical characterization of glass fiber‐grewia optiva fiber reinforced hybrid polymer composite fabricated by vacuum assisted resin transfer moulding (2023)

AbstractThe natural and synthetic fibers are combined in a single composite to achieve a balance between the desired strength and cost considerations. In this study, the vacuum resin transfer moulding process was used to prepare an epoxy‐based composite. The composite consisted of grewia optiva as the natural fiber and glass fiber as the synthetic fiber, both with a fixed weightage of 10 %. Dolomite was used as a filler with varying content (0 %, 5 %, 10 %, and 15 weight %). The physical, mechan

Development of an Epoxy Carbon Fiber Reinforced Roof Frame Using the High Pressure Resin Transfer Molding (HP-RTM) Process (2020)

<div class="section abstract"><div class="htmlview paragraph">Composites technology for the automotive market continues to advance rapidly. Increasing knowledge of composite design, simulation tools, new materials and process equipment are all contributing to make composites better performing and more affordable for mass-produced vehicles. In particular, the high pressure resin transfer molding (HP-RTM) and related liquid compression molding (LCM) processes are enabling manufacturers

SSR marker-based genetic diversity and marker-trait association analysis in aromatic rice (Oryza sativa) landraces (2023)

The present study on SSR marker-based genetic diversity and marker-trait association analysis in aromatic rice (Oryza sativa L.) landraces was carried out at R. H. Richharia Research Laboratory, Indira Gandhi Krishi Vishwavidyalaya, Raipur, Chhattisgarh during 2020. A total of 25 PCR-based simple sequence repeats (SSR) markers were evaluated in a set of 90 aromatic rice landraces along with 6 checks which includes 1 non-aromatic and 5 aromatic check varieties. Phenotypic data for marker-trait as

SSR Marker-Based Insights into Genetic Diversity and Population Structure of Rice (Oryza sativa L.) Germplasm (2025)

Rice, one of the most important cereal crops, serves as a staple food for over half of the global population. Chhattisgarh often referred to as “Rice bowl of India” possesses immense genetic diversity in rice.  Genetic diversity represents the heritable variation within and between populations of organisms and is a pre-requisite for improvement of any crop species. Genetic diversity defines all the available variability and desirable alleles in any crop species/ population which may be exploited

Molecular diversity analysis of rice (Oryza sativa L.) genotypes using RAPD and SSR marker (2022)

Random Amplified Polymorphic DNA (RAPD) and Simple Sequence Repeat (SSR) molecular markers were used for detecting the genetic variability of 20 rice genotypes using 79 SSRs and 30 RAPD primers. Among primers used, a set of 16 SSR and 14 RAPD markers showed polymorphism, and banding patterns were scored as 1 (present) or 0 (absent) in the datasheet which was further analyzed by using Jaccard’s similarity coefficient and SAHN clustering. The number of alleles, PIC value, and heterozygosity for in

Molecular Diversity Analysis and Screening of Drought Tolerance Rice (Oryza sativa L.) based on Morpho-physiological and SSR Marker (2025)

Background: Drought prone areas have been increasing day by day because of raising temperature or heat . The assessment of genetic divergence existing in the germplasm collections is very important for success of hybridization programme leading to development of high yielding varieties under drought stress condition. Methods: The present investigation comprising of 123 rice genotypes was carried out at LPU Phagwara punjab in Kharif 2022 and plants were grown in augmented design under controlled

Genetic structure and diversity of cannabis (Cannabis sativa L.) populations from northern Morocco through genomic SSR analysis (2023)

Morocco has a long history of domesticating cannabis and refuges a local Beldia population, which lacks detailed information on genetic diversity. In this study, the genetic diversity of cannabis grown in four Moroccan regions was assessed with six genomic SSR markers involving two cannabis populations: the local Beldia and the introduced Critical variety. A total of 111 alleles were detected, with an average of 18.5 alleles /locus. Several genetic diversity indices were measured for both popula